| People | Locations | Statistics |
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| Seuring, Stefan |
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| Nor Azizi, S. |
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| Pato, Margarida Vaz |
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| Kölker, Katrin |
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| Huber, Oliver |
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| Király, Tamás |
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| Spengler, Thomas Stefan |
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| Al-Ammar, Essam A. |
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| Dargahi, Fatemeh |
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| Mota, Rui |
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| Mazalan, Nurul Aliah Amirah |
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| Macharis, Cathy | Brussels |
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| Arunasari, Yova Tri |
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| Nunez, Alfredo | Delft |
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| Bouhorma, Mohammed |
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| Bonato, Matteo |
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| Fitriani, Ira |
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| Autor Correspondente Coelho, Sílvia. |
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| Pond, Stephen |
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| Okwara, Ukoha Kalu |
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| Toufigh, Vahid |
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| Campisi, Tiziana | Enna |
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| Ermolieva, Tatiana |
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| Sánchez-Cambronero, Santos |
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| Agzamov, Akhror |
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Gadegbeku, Blandine
in Cooperation with on an Cooperation-Score of 37%
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Publications (10/10 displayed)
- 2023Prescribed anti-glaucoma medication consumption and road traffic crashcitations
- 2019Trends in benzodiazepine anxiolytics and z-hypnotics use among French drivers involved in road traffic crashes from 2005 to 2015: a responsibility case-control studycitations
- 2018Abdominopelvic injuries due to road traffic accidents: Characteristics in a registry of 162,695 victimscitations
- 2017Road traffic crash risk associated with prescription of hydroxyzine and other sedating H1-antihistamines: A responsibility and case-crossover studycitations
- 2016Road traffic crash risk associated with benzodiazepine and z-hypnotic use after implementation of a colour-graded pictogram: a responsibility studycitations
- 2014Road Traffic Injuries Involving Illegal Blood Alcohol Levels and Psychoactive Drug Use in Côte d'Ivoire: A Hospital-based Studycitations
- 2013Prescription of antiepileptics and the risk of road traffic crash.citations
- 2012Road traffic crashes and prescribed methadone and buprenorphine: A french registry-based case–control studycitations
- 2010Prescription medicines and the risk of road traffic crashes: a French registry-based study.citations
- 2009The burden of road traffic accidents in a French Departement: the description of the injuries and recent changes.citations
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article
Road traffic crashes and prescribed methadone and buprenorphine: A french registry-based case–control study
Abstract
Background: Opioids have been shown to impair psychomotor and cognitive functioning in healthy volunteers with no history of opioid abuse. Few or no significant effects have been found in opioid-dependant patients in experimental or driving simulation studies. The risk of road traffic crash among patients under buprenorphine or methadone has not been subject to epidemiological investigation so far. The objective was to investigate the association between the risk of being responsible for a road traffic crash and the use of buprenorphine and methadone. Methods: Data from three French national databases were extracted and matched: the national health care insurance database, police reports, and the national police database of injurious crashes. Case-control analysis comparing responsible versus non responsible drivers was conducted. Results: 72,685 drivers identified by their national health care number, involved in an injurious crash in France over the July 2005 to May 2008 period. The 196 drivers exposed to buprenorphine or methadone on the day of crash were young, essentially males, with an important co-consumption of other substances (alcohol and benzodiazepines). Injured drivers exposed to buprenorphine or methadone on the day of crash, had an increased risk of being responsible for the crash (odds ratio (OR)=2.02, 95% confidence interval (CI): 1.40, 2.91). Conclusions: Users of methadone and buprenorphine were at increased risk of being responsible for injurious road traffic crashes. This risk is probably the combined result of risky behaviors and treatments.
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