| People | Locations | Statistics |
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| Seuring, Stefan |
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| Nor Azizi, S. |
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| Pato, Margarida Vaz |
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| Kölker, Katrin |
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| Huber, Oliver |
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| Király, Tamás |
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| Spengler, Thomas Stefan |
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| Al-Ammar, Essam A. |
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| Dargahi, Fatemeh |
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| Mota, Rui |
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| Mazalan, Nurul Aliah Amirah |
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| Macharis, Cathy | Brussels |
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| Arunasari, Yova Tri |
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| Nunez, Alfredo | Delft |
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| Bouhorma, Mohammed |
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| Bonato, Matteo |
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| Fitriani, Ira |
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| Autor Correspondente Coelho, Sílvia. |
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| Pond, Stephen |
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| Okwara, Ukoha Kalu |
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| Toufigh, Vahid |
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| Campisi, Tiziana | Enna |
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| Ermolieva, Tatiana |
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| Sánchez-Cambronero, Santos |
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| Agzamov, Akhror |
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Gadegbeku, Blandine
in Cooperation with on an Cooperation-Score of 37%
Topics
Publications (10/10 displayed)
- 2023Prescribed anti-glaucoma medication consumption and road traffic crashcitations
- 2019Trends in benzodiazepine anxiolytics and z-hypnotics use among French drivers involved in road traffic crashes from 2005 to 2015: a responsibility case-control studycitations
- 2018Abdominopelvic injuries due to road traffic accidents: Characteristics in a registry of 162,695 victimscitations
- 2017Road traffic crash risk associated with prescription of hydroxyzine and other sedating H1-antihistamines: A responsibility and case-crossover studycitations
- 2016Road traffic crash risk associated with benzodiazepine and z-hypnotic use after implementation of a colour-graded pictogram: a responsibility studycitations
- 2014Road Traffic Injuries Involving Illegal Blood Alcohol Levels and Psychoactive Drug Use in Côte d'Ivoire: A Hospital-based Studycitations
- 2013Prescription of antiepileptics and the risk of road traffic crash.citations
- 2012Road traffic crashes and prescribed methadone and buprenorphine: A french registry-based case–control studycitations
- 2010Prescription medicines and the risk of road traffic crashes: a French registry-based study.citations
- 2009The burden of road traffic accidents in a French Departement: the description of the injuries and recent changes.citations
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article
Prescription of antiepileptics and the risk of road traffic crash.
Abstract
Studies assessing the impact of epilepsy and its medication on the risk of road traffic crashes have shown inconsistent results. The aim in this study was to assess this risk using French databases. Data from three French national databases were extracted and matched: the national health care insurance database, police reports, and the national police database of injurious crashes. Only antiepileptics prescribed predominantly in epilepsy were studied (phenobarbital, phenytoin, ethosuximide, valproic acid, vigabatrin, tiagabin, levitiracetam, zonisamide, and lacosamide). A case-control analysis comparing responsible and non-responsible drivers and a case-crossover analysis were performed. Drivers (72 685) involved in an injurious crash in France between July 2005 and May 2008, were included. Drivers exposed to prescribed antiepileptic medicines (n = 251) had an increased risk of being responsible for a crash (OR 1.74 [1.29-2.34]). The association was also significant for the most severe epileptic patients (n = 99; OR = 2.20 [1.31-3.69]). Case-crossover analysis found no association between crash risk and treatment prescription. Patients with prescription of antiepileptic drugs should be cautioned about their potential risk of road traffic crash. This risk is however more likely to be related to seizures than to the effect of antiepileptic medicines.
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